Names of bitter apple in various languages of the world are also given. The fruits are recognized for their wide range of medicinal uses and promising pharmaceutical potential. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon c. Homeopathy a homeopathic remedy used for colic, neuralgia caused by suppressed emotions, gastric pain, headaches accompanied by nausea and vomiting, gout, rheumatic complaints, and vertigo. Citrullus colocynthis cct, also known as bitter apple, wild gourd, tumba and wine of sodom, is known for its medicinal value since long. The present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of extracts and chemicals identified from citrullus colocynthis. Uses dried pulp of unripe fruit is used medicinally for its drastic purgative and hydragogue cathartic action on the intestinal tract. Therapeutic effects of citrullus colocynthis fruit in patients with type ii. Citrullus colocynthis as the cause of acute rectorrhagia. Flowers are in small flowers are in small with yellow color and the fruit is very bitter, there are several medicinal uses of this plants. Indeed, if you will imagine a watermelon vine bearing a small, hard fruit with a bitter pulp, you. This plant tends to control kapha and pitta doshas. Colocynth citrullus colocynthis flesh extract suppresses. Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins.
The citrullus colocynthis extract significantly lowered the formation of granuloma tissue in chronic inflammation model. Citrullus colocynthis has the traditional use in remedy for cancer. Enhancement of callus induction and cucurbitacin content in. Citrullus colocynthis bitter apple ayurvedic properties. Phytochemical analysis of a folklore medicinal plant citrullus colocynthis l bitter apple c.
Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia. Bitter apple common names bitter apple trees are also known by a host of common. Citrullus colocynthis plant was traditionally used for the treatment of diabetes in sabzevar city, iran. The fruit of citrullus colocynthis is medicinal and nutraceutical values sawaya. The bitter apple is a vinelike plant commonly found in asia and the mediterranean basin. This powder is so inflammable that the arabs collect it to use as kindling. Schrad is a valuable plants from cucurbitaceae family, widely distributed in the barren region, is a nonhardy, herbaceous perennial vine, branched from the base 4.
These plants have lemonsized fruits which are known for their medicinal properties. Enhancement of callus induction and cucurbitacin content in citrullus colocynthis l. Death has resulted from a dose of 1 12 teaspoonsful of the powder. Jonathan hardy discusses two patients treated with medicines in the cucumber family in recent years we have developed our homeopathic understanding of remedies in groups and families. Colocynth citrullus colocynthis uses, dosage, side effects. The medicinal plants are equally used in the cosmetic, perfumery and food industries 7. We have found, for example, that remedies which come from the same family of plants all share a number of characteristics. Uses, side effects, interactions, dosage, and warning. Jan 15, 2018 colocynth indravaruni, bitter apple is a great herbal plant with many useful properties. Citrullus colocynthis an overview sciencedirect topics.
Effects of alkaloid rich extract of citrullus colocynthis. A qualitative analysis was performed for the identification of the presence. Four patients with colocynth intoxication are presented. It is also used in combination products for treating liver and gallbladder ailments. The species is monoecious individual flowers are either male or female, but both sexes can be found on the same plant and is pollinated by insects. Despite serious safety concerns, colocynth is used for diabetes, high cholesterol and blood fats called triglycerides, constipation, and tuberculosis. Persons familiar with the common watermelon vine need no description of the plant which produces colocynth apples. Phytochemical analysis of a folklore medicinal plant citrullus. Colocynthis tends to be the most beneficial as a homeopathic remedy for those who have suppressed anger. Several bioactive chemical constituents from fruits were recorded, such as. Citrullus colocynthis definition of citrullus colocynthis. However, seed germination is poor due to the extreme xeric conditions, so vegetative propagation is more common and successful in nature. The fruit pulp of colocynth has medicinal properties while the seeds have. Citrullus colocynthis supplement health benefits, dosage.
The fruits of citrullus colocynthis have traditionally been used for the treatment of diseases such as diabetes. It was banned by the food and drug administration in 1991 taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. The highest antioxidant and free radical scavenging ability of the fruit extract. The fruit pulp of colocynth has medicinal properties while the seeds. May 10, 2010 colocynthis works well for sharp pains down the outer side of the thigh, leg, or foot. Physicochemical properties of citrullus colocynthis seed oil. Issn phytochemical analysis of a folklore medicinal plant. Pdf the present study reveals the medicinal uses, chemical compositions and examines recent. Citrullus colocynthis fruits were also traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes 47. To study the phytochemical screening of different extracts from citrullus colocynthis c. Phytochemical screening and free radical scavenging activity. These pains may be accompanied by a backache and may even cause some sort of numbness at certain points. Chemical constituents and pharmacological effects of. Pdf medicinal utility of melon citrullus colocynthis l.
In the present study citrullus colocynthis is a very important medicinal plant which is used by various tribes for treatment of many. Sekar abstract phytochemical screening of citrullus colocynthis belonging to the family cucurbitaceae was carried out for finding its medicinal values. When the fruit is ripe its pulp dries to form a powder used as a bitter medicine and drastic purgative. The second edition of an excellent guide to the edible uses of plants, though it does not give any details of cultivation etc. Report by journal of the alabama academy of science.
Bitter apple herb uses, benefits, cures, side effects, nutrients. Learn more about colocynth uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain colocynth. The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. Flowers are in small flowers are in small with yellow color and the fruit is.
Autecological studies on citrullus colocynthis species in. Egusi seed is botanically known as citrullus colocynthis curcurbita citrullus l. Herbal medicinal importance of citrullus lanatus mentioned in the ahadith. Colocynth is used on the skin for nerve pain in people with diabetes. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. Phytochemical screening, total content of polyphenols and. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. Medicinal uses of different parts of citrullus colocynthis. Bitter apple scientific name the scientific name for this plant is citrullus colocynthis. Uses, benefits, cures, side effects, nutrients in bitter apple. Citrullus colocynthis fruits are generally documented for its broad range of pharmaceutical uses as well as medicinal and. Citrullus colocynthis l is a common annual wild plant, procumbent herb with simple tendrils.
Based on the above findings, the researchers agreed that citrullus colocynthis is suitable for use as an antiinflammatory agent. Citrullus colocynthis is a medicinal plant that has anticancer property mediated by apoptosis. Chemical constituents and pharmacological effects of citrullus. Schrad is a valuable cucurbit plant, widely distributed in the desert areas of the world.
It was banned by the food and drug administration fda in 1991. Journal of medicinal plants studies ethnobotanical studies of. Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits was investigated. Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. Cucumis melo has been shown to possess useful medicinal properties such as analgesic, antiinflammatory, antioxidant, free radical scavenging, antiplatelet, antiulcer, anticancer, anti. Colocynth definition of colocynth by the free dictionary.
Citrullus colocynthis, a member of the cucurbitaceae family, is widely distributed in north africa. Colocynthis definition of colocynthis by medical dictionary. Medicinal action and uses it is a powerful drastic hydragogue cathartic producing, when given in large doses, violent griping with, sometimes, bloody discharges and dangerous inflammation of the bowels. Science and technology, general agricultural chemicals antimitotic agents antineoplastic agents fertilizers research food additives germination liquid chromatography phytochemicals plant. Jun 14, 2018 citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally. The present study aimed to investigate the antiobesity effect of the ethanol extract of colocynth flesh fcee in 3t3l1. Citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally. Safety evaluation studies of citrullus colocynthis for. It is known by various names such as bitter cucumber, pumpkin seeds, egusi melon, vine of sodom plant, wild gourd, bitter apple, colocynth or desert gourd. Medicinal the dried, unripe fruit pulp constitutes the drug colocynth, which is a very strong laxative.
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